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Sixty elderly men were put on various Ostarine dosages 3 months, it was found that simply taking 3mg of Ostarine per day led to an increase in muscle mass by 1.74 kg over the 3-months group. The same dose (35mg) also led a gain in body mass by 4.35 kg over the 3-months interval.

As well as increasing muscle mass weight gain, the study showed that daily Ostarine supplementation also was able to maintain muscle strength within a 2-week period.

According to Dr. John M. Hines, PhD, clinical research professor at the University of California at Davis, the drug was well tolerated by both subjects the scientists, although this study should give some caution when trying any supplement to do with muscle repair.

«This may not be as common as I would like,» he said. «The reason we tested the supplement is because that is so effective at increasing muscle mass other things, but it doesn’t appear to increase the strength of any muscle.»

Dr. Hines added that it may take a long period of time the body to get used to the changes it sees in the muscle, if the people taking the diet supplement are already over 30 years old.

«I think there’s an issue with the longevity question in terms of the effects of age,» he said. «The body looks good at the time that you start to get into a muscle-specific injury so long as you are in good mental physical health,» so the effects could start to wear off quickly.

Researchers found that the drug was more effective than regular Ostarine. For instance, on day one, subjects treated with Ostarine improved muscle mass by 8% compared to 30mg of Ostarine, but on day three, improvements in muscle strength by 9%.

Dr. Hines did caution that the study does not mean Ostarine is safe nor is it wise to use when taking supplements.

«That said, this is a really interesting study that is taking two different classes of drugs,» he said. «One is to assess whether there is a dose-related effect that you would not see without this. In fact we are quite familiar with many pharmacological properties of the drugs we are testing, many of which are quite positive.»

Read the full article in the Journal of Clinical Endocrinology Metabolism.

Source:

UCSB Journal of Clinical Endocrinology Metabolism

ScienceDaily: Muscle-Replacement Therapy May Improve Muscle Mass

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